Science Journal of Applied Mathematics and Statistics

| Peer-Reviewed |

Empowerment Through Skill Acquisition and Its Impact on ART Adherence Among HIV-Positive Adults in Lagos, Nigeria during the COVID-19 Pandemic

Received: 5 September 2023    Accepted: 20 September 2023    Published: 9 October 2023
Views:       Downloads:

Share This Article

Abstract

This study investigates the impact of a skill acquisition intervention on Antiretroviral Therapy (ART) adherence among HIV-positive adults in Lagos, Nigeria during the COVID-19 pandemic. The research explores demographic characteristics, changes in adherence rates before and after the intervention and the effectiveness of the intervention. A total of 50 participants were divided into experimental and control groups. Demographic data, including age, gender, income, and education were collected. ART adherence was measured before and after the intervention. Statistical analysis included descriptive statistics, Wilcoxon signed ranks tests and Mann-Whitney U tests. Before the intervention, the control group exhibited higher ART adherence rates compared to the experimental group. However, both groups showed significant improvements in adherence after the intervention. The intervention effectively narrowed the adherence gap between the groups. Wilcoxon signed ranks tests confirmed significant improvements in adherence in both groups before and after the intervention. Mann-Whitney U test results indicated that before the intervention, the control group had higher ART adherence rates compared to the experimental group. However, after the intervention, the Mann-Whitney U test revealed a significant difference in ART adherence between the experimental and control groups. The experimental group had higher adherence rates after the intervention compared to the control group. This study highlights the positive impact of skill acquisition interventions on ART adherence among HIV-positive adults in Lagos, Nigeria. The intervention effectively improved adherence rates and reduced disparities between groups. These findings emphasize the importance of scaling up similar interventions in HIV care programmes. However, future research with larger samples and longer follow-up periods is recommended to validate and expand on these results.

DOI 10.11648/j.sjams.20231102.12
Published in Science Journal of Applied Mathematics and Statistics (Volume 11, Issue 2, April 2023)
Page(s) 37-43
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

HIV, Antiretroviral Therapy, Adherence, Skill Acquisition, COVID-19, Empowerment

References
[1] Bhaskaran K, Hamouda O, Sannes M, Boufassa F, Johnson AM, Lambert P C, et al. Changes in the risk of death after HIV seroconversion compared with mortality in the general population. JAMA, Pub. Med. 2008; 300 (1): 51- 9.
[2] Wing EJ. HIV and aging. Int. J. Infect. Dis. 2016; 53: 61–68.
[3] Simona AI, Diana GI, Gheorghita J. improving the adherence to antiretroviral therapy, a difficult but essential task for a successful HIV treatment-clinical points of view and practical considerations. Front Pharmacol. 2017; 8: 831.
[4] Miller LG, Hays RD. Adherence to combination antiretroviral therapy: synthesis of the literature and clinical implications. AIDS Read. 2000; 10: 177–85.
[5] Chesney M. Adherence to HAART regimens. AIDS Patient Care & STDS. 2003; 17, 169–177.
[6] Ortego C, Huedo-Medina TB, Santos P, Rodrígue E, Sevilla L, Warren M, et al. Sex differences in adherence to highly active antiretroviral therapy: a meta-analysis. AIDS Care. 2012; 24, 1519–1534.
[7] Murphy EL, Collier AC, Kalish LA, Assmann SF, Para MF, Flanigan TP, et al. Highly active antiretroviral therapy decreases mortality and morbidity in patients with advanced HIV disease. Ann Intern Med. 2001; 135 (1): 17–26.
[8] Glikman D, Walsh L, Valkenburg J, Mangat PD, Marcinak JF. Hospital-based directly observed therapy for HIV-infected children and adolescents to assess adherence to antiretroviral medications. Pediatrics. 2007; 119: 1142–1148.
[9] McKinney RE Jr, Rodman J, Hu C, Britto P, Hughes M, Smith ME et al. Long-term safety and efficacy of a once-daily regimen of emtricitabine, didanosine, and efavirenz in HIV-infected, therapy-naive children and adolescents. Pediatric AIDS Clinical Trials Group Protocol P1021. 2007; 120 (2): e416–23.
[10] Puccio JA, Belzer M, Olson J, Martinez M, Salata C, Tuker D et al. The use of cell phone reminder calls for assisting HIV-infected adolescents and young adults to adhere to highly active antiretroviral therapy: a pilot study. AIDS Patient Care STDS. 2006; 20 (6): 438–44.
[11] Rogers AS, Miller S, Murphy DA, Tanney M, Fortune T. The TREAT (Therapeutic Regimens Enhancing Adherence in Teens) program: theory and preliminary results. J Adolesc Health. 2001; 29 (3 Suppl): 30–38.
[12] Martins NI, Damian KA. Empowering the rural poor through vocational skills acquisition: Nasarawa state in focus. International Journal of Development and Sustainability. 2017; 6 (3): 115-129.
[13] Spratt ES, Papa CE, Mueller M, Patel S, Killeen T, Maher E, et al. Using Technology to improve adherence to HIV medications in transitional age youth: Research Reviewed, Methods Tried, Lessons Learned. J Gen Med. 2017; 1 (1): 1 – 8.
[14] Ratchaneekorn K, Nongyao K, Jittaporn C, Richard MG. Effect of an empowerment intervention on antiretroviral drug adherence in Thai youth. Behavioural Medicine: 2015; 41 (4): 186-194.
[15] Adewale B, Raheem T, Osuolale K, Chukwu E, Liboro G, Odewale E, et al. Utility of temperature measurement using non-contact infrared thermometer in detecting elevated temperature as an infection control measure in the era of Covid-19. African Journal of Medical and Health Sciences. 2021; 20 (6): 80- 84.
[16] Coronavirus disease 2019 (covid-19) and HIV: key issues and actions. Prepared by The UNAIDS Cosponsors Regional Group (UCRG) for Latin America and the Caribbean. 20 March, 2020.
[17] Sharma SK, Mudgal SK, Thakur K, Gaur R. How to calculate sample size for observational and experimental nursing research studies? Natl J Physiol Pharm Pharmacol 2020; 10 (01): 1-8.
[18] Mills EJ, Nachega JB, Bangsberg DR, Singh S, Rachlis B, et al. (2006). Adherence to HAART: a systematic review of developed and developing nation patient-reported barriers and facilitators. PLoS Med, 3 (11), e438. doi: 10.1371/journal.pmed.0030438.
[19] Sabin LL, Mansfield L, DeSilva MB, Vian T, Li Z, et al. (2018). Why it Worked: Participants' Insights into an mHealth Antiretroviral Therapy Adherence Intervention in China. Open AIDS J, 12, 20-37.
[20] Ware NC, Idoko J, Kaaya S, Biraro IA, Wyatt MA, et al. (2009). Explaining adherence success in sub-Saharan Africa: an ethnographic study. PLoS Med, 6 (1), e11.
Cite This Article
  • APA Style

    Kazeem Adewale Osuolale, Adesola Zaidat Musa, Ifeoma Idigbe, Ozichu Sabdat Ekama, Wasiu Ademola Adekunle, et al. (2023). Empowerment Through Skill Acquisition and Its Impact on ART Adherence Among HIV-Positive Adults in Lagos, Nigeria during the COVID-19 Pandemic. Science Journal of Applied Mathematics and Statistics, 11(2), 37-43. https://doi.org/10.11648/j.sjams.20231102.12

    Copy | Download

    ACS Style

    Kazeem Adewale Osuolale; Adesola Zaidat Musa; Ifeoma Idigbe; Ozichu Sabdat Ekama; Wasiu Ademola Adekunle, et al. Empowerment Through Skill Acquisition and Its Impact on ART Adherence Among HIV-Positive Adults in Lagos, Nigeria during the COVID-19 Pandemic. Sci. J. Appl. Math. Stat. 2023, 11(2), 37-43. doi: 10.11648/j.sjams.20231102.12

    Copy | Download

    AMA Style

    Kazeem Adewale Osuolale, Adesola Zaidat Musa, Ifeoma Idigbe, Ozichu Sabdat Ekama, Wasiu Ademola Adekunle, et al. Empowerment Through Skill Acquisition and Its Impact on ART Adherence Among HIV-Positive Adults in Lagos, Nigeria during the COVID-19 Pandemic. Sci J Appl Math Stat. 2023;11(2):37-43. doi: 10.11648/j.sjams.20231102.12

    Copy | Download

  • @article{10.11648/j.sjams.20231102.12,
      author = {Kazeem Adewale Osuolale and Adesola Zaidat Musa and Ifeoma Idigbe and Ozichu Sabdat Ekama and Wasiu Ademola Adekunle and Abideen Olurotimi Salako and Oluchukwu Nkem Iwegbu and Abdulrasheed Oladele Oba and Wakilat Afolashade Tijani and Oliver Chukwujekwu Ezechi and Babatunde Lawal Salako},
      title = {Empowerment Through Skill Acquisition and Its Impact on ART Adherence Among HIV-Positive Adults in Lagos, Nigeria during the COVID-19 Pandemic},
      journal = {Science Journal of Applied Mathematics and Statistics},
      volume = {11},
      number = {2},
      pages = {37-43},
      doi = {10.11648/j.sjams.20231102.12},
      url = {https://doi.org/10.11648/j.sjams.20231102.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjams.20231102.12},
      abstract = {This study investigates the impact of a skill acquisition intervention on Antiretroviral Therapy (ART) adherence among HIV-positive adults in Lagos, Nigeria during the COVID-19 pandemic. The research explores demographic characteristics, changes in adherence rates before and after the intervention and the effectiveness of the intervention. A total of 50 participants were divided into experimental and control groups. Demographic data, including age, gender, income, and education were collected. ART adherence was measured before and after the intervention. Statistical analysis included descriptive statistics, Wilcoxon signed ranks tests and Mann-Whitney U tests. Before the intervention, the control group exhibited higher ART adherence rates compared to the experimental group. However, both groups showed significant improvements in adherence after the intervention. The intervention effectively narrowed the adherence gap between the groups. Wilcoxon signed ranks tests confirmed significant improvements in adherence in both groups before and after the intervention. Mann-Whitney U test results indicated that before the intervention, the control group had higher ART adherence rates compared to the experimental group. However, after the intervention, the Mann-Whitney U test revealed a significant difference in ART adherence between the experimental and control groups. The experimental group had higher adherence rates after the intervention compared to the control group. This study highlights the positive impact of skill acquisition interventions on ART adherence among HIV-positive adults in Lagos, Nigeria. The intervention effectively improved adherence rates and reduced disparities between groups. These findings emphasize the importance of scaling up similar interventions in HIV care programmes. However, future research with larger samples and longer follow-up periods is recommended to validate and expand on these results.},
     year = {2023}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Empowerment Through Skill Acquisition and Its Impact on ART Adherence Among HIV-Positive Adults in Lagos, Nigeria during the COVID-19 Pandemic
    AU  - Kazeem Adewale Osuolale
    AU  - Adesola Zaidat Musa
    AU  - Ifeoma Idigbe
    AU  - Ozichu Sabdat Ekama
    AU  - Wasiu Ademola Adekunle
    AU  - Abideen Olurotimi Salako
    AU  - Oluchukwu Nkem Iwegbu
    AU  - Abdulrasheed Oladele Oba
    AU  - Wakilat Afolashade Tijani
    AU  - Oliver Chukwujekwu Ezechi
    AU  - Babatunde Lawal Salako
    Y1  - 2023/10/09
    PY  - 2023
    N1  - https://doi.org/10.11648/j.sjams.20231102.12
    DO  - 10.11648/j.sjams.20231102.12
    T2  - Science Journal of Applied Mathematics and Statistics
    JF  - Science Journal of Applied Mathematics and Statistics
    JO  - Science Journal of Applied Mathematics and Statistics
    SP  - 37
    EP  - 43
    PB  - Science Publishing Group
    SN  - 2376-9513
    UR  - https://doi.org/10.11648/j.sjams.20231102.12
    AB  - This study investigates the impact of a skill acquisition intervention on Antiretroviral Therapy (ART) adherence among HIV-positive adults in Lagos, Nigeria during the COVID-19 pandemic. The research explores demographic characteristics, changes in adherence rates before and after the intervention and the effectiveness of the intervention. A total of 50 participants were divided into experimental and control groups. Demographic data, including age, gender, income, and education were collected. ART adherence was measured before and after the intervention. Statistical analysis included descriptive statistics, Wilcoxon signed ranks tests and Mann-Whitney U tests. Before the intervention, the control group exhibited higher ART adherence rates compared to the experimental group. However, both groups showed significant improvements in adherence after the intervention. The intervention effectively narrowed the adherence gap between the groups. Wilcoxon signed ranks tests confirmed significant improvements in adherence in both groups before and after the intervention. Mann-Whitney U test results indicated that before the intervention, the control group had higher ART adherence rates compared to the experimental group. However, after the intervention, the Mann-Whitney U test revealed a significant difference in ART adherence between the experimental and control groups. The experimental group had higher adherence rates after the intervention compared to the control group. This study highlights the positive impact of skill acquisition interventions on ART adherence among HIV-positive adults in Lagos, Nigeria. The intervention effectively improved adherence rates and reduced disparities between groups. These findings emphasize the importance of scaling up similar interventions in HIV care programmes. However, future research with larger samples and longer follow-up periods is recommended to validate and expand on these results.
    VL  - 11
    IS  - 2
    ER  - 

    Copy | Download

Author Information
  • Grant, Monitoring and Evaluation Unit (Biostatistics), Nigerian Institute of Medical Research, Lagos, Nigeria

  • Grant, Monitoring and Evaluation Unit (Biostatistics), Nigerian Institute of Medical Research, Lagos, Nigeria

  • Clinical Sciences Department, Nigerian Institute of Medical Research, Lagos, Nigeria

  • Clinical Sciences Department, Nigerian Institute of Medical Research, Lagos, Nigeria

  • Department of Economics, University of Ibadan, Ibadan, Nigeria

  • Clinical Sciences Department, Nigerian Institute of Medical Research, Lagos, Nigeria

  • Finance and Accounts Department, Nigerian Institute of Medical Research, Lagos, Nigeria

  • Clinical Sciences Department, Nigerian Institute of Medical Research, Lagos, Nigeria

  • Grant, Monitoring and Evaluation Unit (Biostatistics), Nigerian Institute of Medical Research, Lagos, Nigeria

  • Clinical Sciences Department, Nigerian Institute of Medical Research, Lagos, Nigeria

  • Clinical Sciences Department, Nigerian Institute of Medical Research, Lagos, Nigeria

  • Sections